Nanorobots built to reach where treatment stops.

Selene Nanorobotics is developing microrobotic technology for active intervention in hard-to-reach biological environments, starting with endodontics.

An early-stage biotechnology company building single-use, catalytic microrobotic kits to eliminate persistent bacterial biofilm inside human root canals.

Operating out of the San Diego ecosystem, our current mission is to address the $1 billion annual economic burden of root canal treatment failures in the United States. By introducing console-free, disposable micro-automation into existing syringe-based irrigation workflows, we provide endodontists with surgical-grade precision at a disposable price point. Founded by Babak Tousifar, the team includes engineers and scientists working across bioengineering, robotics, and computational science.

How it works

Six design principles behind Selene's microrobotic platform.

Multi-Modal Action

Mechanical disruption paired with localized reactive oxygen species — a payload-ready platform built to carry future active agents.

Autonomous Microrobots

Chemical propulsion with magnetic steering, designed for precise navigation through the root canal system.

Minimally Invasive

No high-pressure irrigation or aggressive instrumentation required.

Deep Cleaning

Engineered to penetrate dentinal tubules and clear the smear layer and biofilm underneath.

Affordable & Accessible

A single-use kit designed for adoption in general dental practices, not just specialist clinics.

Safe & Retrievable

Biocompatible, self-degrading materials, with optional magnetic retrieval built into the design.

Scientific foundation

Our platform leverages titanium dioxide/platinum (TiO₂/Pt) micro-engines. In published laboratory dental-biofilm models (Villa et al., 2020), this catalytic mechanism achieved up to 95% bacterial killing within a five-minute window.

Read the study
TiO2 shell
Pt nanoparticles
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IP position

Selene holds temporary rights and a commercial-license negotiation framework via an executed Evaluation License Agreement (ELA) with UC San Diego, covering the membrane-template microtube-engine patent family.

Recognition

Programs, funding, and awards Selene has been selected for.

22

Customer interviews completed through NSF I-Corps Regional, part of the 2025 UCSD MedTech Accelerator Stage 1 program.

10+

Letters of support and collaboration from clinical, regulatory, and vendor partners across Selene's growing ecosystem.

UC San Diego
Institute for the Global Entrepreneur
NSF I-Corps
California Life Sciences
HomeLab, powered by LabFellows
NAMSA
Montana State University
Center for Biofilm Engineering, Montana State University
Procopio
America's SBDC California, San Diego and Imperial Network
The Dental Specialists
MCRA, an IQVIA business
University of San Diego
Qualcomm Institute
ACTRI
NANO3
CONNECT
Origami Air
Aquillius

Talk to us

Interested in what we're building, or want to join the team? Reach out on LinkedIn or by email.

San Diego, California